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Literature summary for 1.2.7.12 extracted from
- Thermodynamics of the formylmethanofuran dehydrogenase reaction in Methanobacterium thermoautotrophicum (1994), Eur. J. Biochem., 226, 811-818.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.008 | - |
oxidized carbamoylviologen | - |
Methanothermobacter thermautotrophicus |  |
| 0.015 | - |
oxidized benzylviologen | - |
Methanothermobacter thermautotrophicus | |
| 0.03 | - |
N-formylmethanofuran | - |
Methanothermobacter thermautotrophicus | |
| 0.04 | - |
oxidized methylviologen | - |
Methanothermobacter thermautotrophicus | |
| 0.1 | - |
methanofuran | - |
Methanothermobacter thermautotrophicus | |
| 0.125 | - |
oxidized 1,1',2,2'-tetramethylviologen | - |
Methanothermobacter thermautotrophicus | |
| 0.4 | - |
reduced 1,1',2,2'-tetramethylviologen | - |
Methanothermobacter thermautotrophicus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Methanothermobacter thermautotrophicus | initial step of methanogenesis | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Methanothermobacter thermautotrophicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| formylmethanofuran + H2O + oxidized carbamoylviologen | - |
Methanothermobacter thermautotrophicus | CO2 + methanofuran + reduced carbamoylviologen | - |
r | |
| formylmethanofuran + oxidized 1,1',2,2'-tetramethylviologen | r | Methanothermobacter thermautotrophicus | CO2 + methanofuran + reduced 1,1',2,2'-tetramethylviologen | - |
? | |
| formylmethanofuran + oxidized benzylviologen + H2O | - |
Methanothermobacter thermautotrophicus | methanofuran + reduced benzylviologen + CO2 | - |
? | |
| formylmethanofuran + oxidized carbamoylmethylviologen + H2O | - |
Methanothermobacter thermautotrophicus | methanofuran + reduced carbamoylmethylviologen + CO2 | - |
? | |
| formylmethanofuran + oxidized methylviologen + H2O | - |
Methanothermobacter thermautotrophicus | methanofuran + reduced methylviologen + CO2 | - |
? | |
| additional information | no reduction of metronidazole, methylene blue, FAD or coenzyme F420 with formylmethanofuran | Methanothermobacter thermautotrophicus | ? | - |
? | |
| additional information | initial step of methanogenesis | Methanothermobacter thermautotrophicus | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 70 | - |
- |
Methanothermobacter thermautotrophicus |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | 70 | 25°C: less than 5% of maximal activity, 60°C: about 90% of maximal activity, 70°C: maximal activity | Methanothermobacter thermautotrophicus |
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