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Literature summary for 1.2.4.1 extracted from

  • Fleige, T.; Fischer, K.; Ferguson, D.J.; Gross, U.; Bohne, W.
    Carbohydrate metabolism in the Toxoplasma gondii apicoplast: localization of three glycolytic isoenzymes, the single pyruvate dehydrogenase complex, and a plastid phosphate translocator (2007), Eukaryot. Cell, 6, 984-996.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21+ cells Toxoplasma gondii

Localization

Localization Comment Organism GeneOntology No. Textmining
apicoplast exclusively localized to the apicoplast Toxoplasma gondii 20011
-
additional information absent in the mitochondrion Toxoplasma gondii
-
-

Organism

Organism UniProt Comment Textmining
Toxoplasma gondii Q1KSF0
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyruvate + CoA + NAD+
-
Toxoplasma gondii acetyl-CoA + CO2 + NADH
-
?
pyruvate + lipoamide
-
Toxoplasma gondii S-acetyldihydrolipoamide + CO2
-
?

Synonyms

Synonyms Comment Organism
PDH subunit E1-beta
-
Toxoplasma gondii
pyruvate dehydrogenase complex,
-
Toxoplasma gondii

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Toxoplasma gondii
thiamine diphosphate
-
Toxoplasma gondii