Inhibitors | Comment | Organism | Structure |
---|---|---|---|
menadione | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.004 | 0.015 | benzaldehyde | - |
Homo sapiens | |
0.008 | 0.014 | N-[(2-dimethylamino)ethyl] acridine-4-carboxamide | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | 2 Fe/S iron centres | Homo sapiens | |
Mo5+ | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | enzyme plays an important role in the biotransformation of drugs and xenobiotics, e.g. antiviral, antimalarial and antitumour compounds and nicotine | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-fluoropyrimidine + H2O + O2 | - |
Homo sapiens | 5-fluorouracil + H2O2 | - |
? | |
benzaldehyde + H2O + O2 | - |
Homo sapiens | benzoic acid + H2O2 | - |
? | |
additional information | enzyme plays an important role in the biotransformation of drugs and xenobiotics, e.g. antiviral, antimalarial and antitumour compounds and nicotine | Homo sapiens | ? | - |
? | |
N-[(2-dimethylamino)ethyl] acridine-4-carboxamide + H2O + O2 | - |
Homo sapiens | N-[(2-dimethylamino)ethyl] acridine-4-carboxamide-9(10H)-acridone + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AO | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
benzaldehyde assay at | Homo sapiens |
37 | - |
N-[(2-dimethylamino)ethyl] acridine-4-carboxamide assay | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
assay at | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0003 | 0.0086 | menadione | - |
Homo sapiens |