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Literature summary for 1.2.1.99 extracted from

  • Ashok, S.; Raj, S.M.; Rathnasingh, C.; Park, S.
    Development of recombinant Klebsiella pneumoniae DELTAdhaT strain for the co-production of 3-hydroxypropionic acid and 1,3-propanediol from glycerol (2011), Appl. Microbiol. Biotechnol., 90, 1253-1265.
    View publication on PubMed
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Application

Application Comment Organism
synthesis 3-hydroxypropionic acid is an important compound from which several commodity and specialty chemicals can be generated. The DELTAdhaT mutant (deletion in gene dhaT, encoding NADH-dependent 1,3-propanediol oxidoreductase) overexpressing PuuC has a potential to coproduce two commercially valuable products, 3-hydroxypropionic acid and 1,3-propanediol Klebsiella pneumoniae

Cloned(Commentary)

Cloned (Comment) Organism
-
 Klebsiella pneumoniae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-hydroxypropionaldehyde + NAD+ + H2O Klebsiella pneumoniae
-
 3-hydroxypropanoate + NADH + 2 H+
-
 ?
3-hydroxypropionaldehyde + NAD+ + H2O Klebsiella pneumoniae DSM 2026
-
 3-hydroxypropanoate + NADH + 2 H+
-
 ?

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae
-
-
-
Klebsiella pneumoniae DSM 2026
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxypropionaldehyde + NAD+ + H2O
-
 Klebsiella pneumoniae 3-hydroxypropanoate + NADH + 2 H+
-
 ?
3-hydroxypropionaldehyde + NAD+ + H2O
-
 Klebsiella pneumoniae DSM 2026 3-hydroxypropanoate + NADH + 2 H+
-
 ?

Synonyms

Synonyms Comment Organism
NAD+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase
-
 Klebsiella pneumoniae
PuuC
-
 Klebsiella pneumoniae