Protein Variants | Comment | Organism |
---|---|---|
E314A | inactive. The conserved Glu447 residue has significantly shifted in the mutant, causing NAD+ to be displaced | Homo sapiens |
S352A | catalytic site including the oxoanion hole and residue Cys348 remain unchanged in the mutant, and the coenzyme maintains its binding position | Homo sapiens |
S352L | inactive. The conserved Glu447 residue has significantly shifted in the mutant, causing NAD+ to be displaced | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P30038 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
P5CDH | - |
Homo sapiens |