Organism | UniProt | Comment | Textmining |
---|---|---|---|
Neurospora crassa | Q1K615 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
apo-4'-lycopenal + NAD+ + H2O | the in vivo substrate of Ylo-1 is apo-4'-lycopenal rather than its cyclic isomer beta-apo-4'-carotenal | Neurospora crassa | apo-4'-lycopenoic acid + NADH + 2 H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
YLO-1 | - |
Neurospora crassa |
General Information | Comment | Organism |
---|---|---|
physiological function | enzyme is involved in the biosynthetic pathway to neurosporaxanthin. First step is the cleavage of 3,4-didehydrolycopene into apo-4'-lycopenal by Cao2, which is then oxidized by YLO-1 to yield apo-4'-lycopenoic acid, the last intermediate in the pathway. The final step is then catalyzed by the cyclase activity of AL-2. An Ylo-1 mutant accumulates three major pigments, i.e. lycopene, apo-4'-lycopenal and apo-4'-lycopenol. The pigments accumulating in the Ylo-1 mutant are non-cyclic and represent lycopene and apolycopenoids, indicating that the in vivo substrate of Ylo-1 is apo-4'-lycopenal rather than its cyclic isomer beta-apo-4'-carotenal | Neurospora crassa |