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Literature summary for 1.2.1.67 extracted from

  • Narbad, A.; Gasson, M.J.
    Metabolism of ferulic acid via vanillin using a novel CoA-dependent pathway in a newly isolated strain of Pseudomonas fluorescens (1998), Microbiology, 144, 1397-1405.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-hydroxy-3-methoxybenzaldehyde + NAD+ + H2O Pseudomonas fluorescens no reduction of vanillic acid to vanillin in crude cell extract observed, metabolism of ferulic acid to vanillic acid 4-hydroxy-3-methoxybenzoate + NADH + H+
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ir
4-hydroxy-3-methoxybenzaldehyde + NAD+ + H2O Pseudomonas fluorescens AN103 no reduction of vanillic acid to vanillin in crude cell extract observed, metabolism of ferulic acid to vanillic acid 4-hydroxy-3-methoxybenzoate + NADH + H+
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ir

Organism

Organism UniProt Comment Textmining
Pseudomonas fluorescens
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Source Tissue

Source Tissue Comment Organism Textmining
cell culture maximal enzyme synthesis, if cells grown in ferulic acid containing medium Pseudomonas fluorescens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-hydroxy-3-methoxybenzaldehyde + NAD+ + H2O no reduction of vanillic acid to vanillin in crude cell extract observed, metabolism of ferulic acid to vanillic acid Pseudomonas fluorescens 4-hydroxy-3-methoxybenzoate + NADH + H+
-
ir
4-hydroxy-3-methoxybenzaldehyde + NAD+ + H2O no reduction of vanillic acid to vanillin in crude cell extract observed, metabolism of ferulic acid to vanillic acid Pseudomonas fluorescens AN103 4-hydroxy-3-methoxybenzoate + NADH + H+
-
ir

Cofactor

Cofactor Comment Organism Structure
NAD+ in absence of NAD+ only 25% oxidation of vanillin observed Pseudomonas fluorescens