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Literature summary for 1.2.1.65 extracted from

  • Singh, R.; Trivedi, V.D.; Phale, P.S.
    Metabolic regulation and chromosomal localization of carbaryl degradation pathway in Pseudomonas sp. strains C4, C5 and C6 (2013), Arch. Microbiol., 195, 521-535 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
SALDH, DNA and amino acid sequence determination and analysis, the gene for SALDH is probably located on the chromosome in strains C4, C5 and C6, sequence comparisons and phylogenetic analysis Pseudomonas sp. C6

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
salicylaldehyde + NAD+ + H2O Pseudomonas sp. C6
-
salicylate + NADH + 2 H+
-
?

Organism

Organism UniProt Comment Textmining
Pseudomonas sp. C6 I3QHK7
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture Pseudomonas sp. strains C4, C5 and C6 utilize carbaryl as the sole source of carbon and energy via 1-naphthol, 1,2-dihydroxynaphthalene, benzalpyruvate, salicylaldehyde, salicylate, gentisate and maleylpyruvate, effects on enzyme activities of the carbaryl degradation pathway, overview. Cells grown on salicylate show poor activity for SALDH. Strains C4, C5 and C6 show low overall salicylaldehyde dehydrogenase activity Pseudomonas sp. C6
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
salicylaldehyde + NAD+ + H2O
-
Pseudomonas sp. C6 salicylate + NADH + 2 H+
-
?

Synonyms

Synonyms Comment Organism
sALDH
-
Pseudomonas sp. C6

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
assay at Pseudomonas sp. C6

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Pseudomonas sp. C6

General Information

General Information Comment Organism
metabolism pathway for the degradation of carbaryl via gentisate, overview. Various enzymes are involved in the metabolic pathway, including salicylaldehyde dehydroganse Pseudomonas sp. C6