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Literature summary for 1.2.1.44 extracted from

  • Ghosh, R.; Choi, B.; Cho, B.K.; Lim, H.S.; Park, S.U.; Bae, H.J.; Natarajan, S.; Bae, H.
    Characterization of developmental- and stress-mediated expression of cinnamoyl-CoA reductase in kenaf (Hibiscus cannabinus L.) (2014), ScientificWorldJournal, 2014, 601845 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.44

Cloned(Commentary)

Cloned (Comment) Organism
gene CCR, sequence comparisons and phylogenetic analysis Hibiscus cannabinus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-coumaroyl-CoA + NADPH + H+ Hibiscus cannabinus
-
 4-coumaraldehyde + CoA + NADP+
-
 ?
feruloyl-CoA + NADPH + H+ Hibiscus cannabinus
-
 coniferaldehyde + CoA + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Hibiscus cannabinus A0A023HHB5
-
-
Hibiscus cannabinus D9ZKR8
-
-

Source Tissue

Source Tissue Comment Organism Textmining
flower
-
 Hibiscus cannabinus
-
leaf young leaf, immature leaf, and mature leaf Hibiscus cannabinus
-
petiole
-
 Hibiscus cannabinus
-
root
-
 Hibiscus cannabinus
-
seedling
-
 Hibiscus cannabinus
-
stem
-
 Hibiscus cannabinus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-coumaroyl-CoA + NADPH + H+
-
 Hibiscus cannabinus 4-coumaraldehyde + CoA + NADP+
-
 ?
feruloyl-CoA + NADPH + H+
-
 Hibiscus cannabinus coniferaldehyde + CoA + NADP+
-
 ?

Subunits

Subunits Comment Organism
? x * 37370, about, sequence calculation Hibiscus cannabinus
More the enzyme contains two highly conserved motifs:NAD(P) binding domain (VTGAGGFIASWMVKLLLEKGY) at N-terminal and probable catalytic domain (NWYCYGK) Hibiscus cannabinus

Synonyms

Synonyms Comment Organism
CCR
-
 Hibiscus cannabinus
HcCCR1
-
 Hibiscus cannabinus
HcCCR2
-
 Hibiscus cannabinus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Hibiscus cannabinus

pI Value

Organism Comment pI Value Maximum pI Value
Hibiscus cannabinus sequence calculation
-
 6.27

Expression

Organism Comment Expression
Hibiscus cannabinus developmental- and stress-mediated expression of cinnamoyl-CoA reductase in Hibiscus cannabinus. HcCCR2 is expressed differentially in response to various stresses, and the highest expression is observed by drought and NaCl treatments additional information
Hibiscus cannabinus developmental- and stress-mediated expression of cinnamoyl-CoA reductase in Hibiscus cannabinus. HcCCR2 is expressed differentially in response to various stresses, and the highest expression is observed by drought and NaCl treatments, transcript expression patterns of HcCCR2 in response to various abiotic stresses, overview additional information
Hibiscus cannabinus the enzyme expression is induced upon stress by salt, drought, abscisic acid, and wounding, as well as by cold, H2O2, methyljasmonate, and salicylic acid up

General Information

General Information Comment Organism
malfunction AtCCR2 expression is increased in Arabidopsis ccr1 mutant and function is partly compensated Hibiscus cannabinus
metabolism the enzyme is involved in the Monolignol biosynthetic pathway in dicotyledonous angiosperms, pathway overview Hibiscus cannabinus