Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | cellular mRNA levels are increased up to 90fold in the presence of glutamate. A minimal concentration of 0.2 M glutamate already stimulates proA gene expression | Halobacillus halophilus |
Application | Comment | Organism |
---|---|---|
additional information | the genes proH encoding pyrroline-5-carboxylate reductase, proJ encoding glutamate-5-kinase, and proA encoding glutamate-5-semialdehyde dehydrogenase form a transcriptional unit. This pro operon is involved in salinity-induced proline biosynthesis | Halobacillus halophilus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | expression of the proA gene is salinity-dependent and reaches a maximum at 2.5 M NaCl | Halobacillus halophilus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Halobacillus halophilus | A7Y114 | strain DSMZ 2266T | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate 5-semialdehyde + phosphate + NADP+ | - |
Halobacillus halophilus | L-5-glutamyl phosphate + NADPH + H+ | - |
? |