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Literature summary for 1.2.1.4 extracted from
- Purification and characterization of two aldehyde dehydrogenases from Pseudomonas aeruginosa (1977), Eur. J. Biochem., 81, 185-192.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| o-Iodosobenzoate | 1 mM, 3 min, complete inhibition | Pseudomonas aeruginosa |  |
| p-hydroxymercuribenzoate | 0.1 mM, 3 min, complete inhibition | Pseudomonas aeruginosa | |
| Sodium acetate | 1 mM, 92% inhibition | Pseudomonas aeruginosa | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | influence of pH-value and buffer of the Km-value for hexanal | Pseudomonas aeruginosa | |
| 0.01 | - |
dodecanal | - |
Pseudomonas aeruginosa | |
| 0.015 | - |
Tetradecanal | - |
Pseudomonas aeruginosa | |
| 0.016 | - |
Undecanal | - |
Pseudomonas aeruginosa | |
| 0.023 | - |
decanal | - |
Pseudomonas aeruginosa | |
| 0.023 | - |
tridecanal | - |
Pseudomonas aeruginosa | |
| 0.025 | - |
Nonanal | - |
Pseudomonas aeruginosa | |
| 0.062 | - |
octanal | - |
Pseudomonas aeruginosa | |
| 0.065 | - |
NADP+ | reaction with pentanal | Pseudomonas aeruginosa | |
| 0.108 | - |
Heptanal | - |
Pseudomonas aeruginosa | |
| 0.25 | - |
hexanal | - |
Pseudomonas aeruginosa | |
| 0.435 | - |
pentanal | - |
Pseudomonas aeruginosa | |
| 2.2 | - |
Butanal | - |
Pseudomonas aeruginosa | |
| 11 | - |
propanal | - |
Pseudomonas aeruginosa | |
| 35 | - |
acetaldehyde | - |
Pseudomonas aeruginosa | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| K+ | activates | Pseudomonas aeruginosa | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 215000 | - |
gel filtration | Pseudomonas aeruginosa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas aeruginosa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Pseudomonas aeruginosa |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Pseudomonas aeruginosa |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -8°C, 16% glycerol, 1 mM dithiothreitol, 12% loss of activity after 6 months | Pseudomonas aeruginosa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetaldehyde + NADP+ + H2O | - |
Pseudomonas aeruginosa | acetate + NADPH + H+ | - |
? | |
| butanal + NADP+ + H2O | - |
Pseudomonas aeruginosa | butyrate + NADPH + H+ | - |
? | |
| decanal + NADP+ | - |
Pseudomonas aeruginosa | decanoate + NADPH | - |
? | |
| dodecanal + NADP+ + H2O | - |
Pseudomonas aeruginosa | dodecanoate + NADPH + H+ | - |
? | |
| formaldehyde + NADP+ + H2O | - |
Pseudomonas aeruginosa | formate + NADPH + H+ | - |
? | |
| heptanal + NADP+ | - |
Pseudomonas aeruginosa | heptanoate + NADPH | - |
? | |
| hexanal + NADP+ | - |
Pseudomonas aeruginosa | hexanoate + NADPH | - |
? | |
| nonanal + NADP+ + H2O | - |
Pseudomonas aeruginosa | nonanoate + NADPH + H+ | - |
r | |
| octanal + NADP+ + H2O | - |
Pseudomonas aeruginosa | octanoate + NADPH + H+ | - |
? | |
| pentanal + NADP+ | - |
Pseudomonas aeruginosa | pentanoate + NADPH | - |
? | |
| propanal + NADP+ + H2O | - |
Pseudomonas aeruginosa | propionate + NADPH + H+ | - |
? | |
| tetradecanal + NADP+ | - |
Pseudomonas aeruginosa | tetradecanoate + NADPH | - |
? | |
| tridecanal + NADP+ | - |
Pseudomonas aeruginosa | tridecanoate + NADPH | - |
? | |
| undecanal + NADP+ | - |
Pseudomonas aeruginosa | undecanoate + NADPH | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | - |
Pseudomonas aeruginosa | |
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