Literature summary for 1.2.1.36 extracted from

Fujiwara, K.; Maekawa, F.; Kikuchi, M.; Takigami, S.; Yada, T.; Yashiro, T.
Expression of retinaldehyde dehydrogenase (RALDH)2 and RALDH3 but not RALDH1 in the developing anterior pituitary glands of rats (2006), Cell Tissue Res., 328, 129-135.

Search for more literature for 1.2.1.36

Cloned(Commentary)

Cloned (Comment)	Organism
into the pGEM-T easy vector, 396-1002	Rattus norvegicus
into the pGEM-T easy vector, bp 1488-2079	Rattus norvegicus
into the pGEM-T easy vector, bp 935-1485	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
retinal + NAD+ + H2O	Rattus norvegicus	-	retinoate + NADH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	P51647	Wistar rat	-
Rattus norvegicus	P51647	Wistar rats	-
Rattus norvegicus	Q63639	Wistar rat	-
Rattus norvegicus	Q63639	Wistar rats	-
Rattus norvegicus	Q8K4D8	Wistar rat	-
Rattus norvegicus	Q8K4D8	Wistar rats	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
anterior pituitary gland	developing pituitary gland	Rattus norvegicus	-
ectoderm	at embryonic day 12.5, RALDH1 mRNA is present in the posterior region of oral ectoderm	Rattus norvegicus	-
ectoderm	at embryonic day 12.5, RALDH2 mRNA is present in part of the anterior oral ectoderm	Rattus norvegicus	-
embryo	-	Rattus norvegicus	-
additional information	no expression of RALDH1 in the rat embryonic pituitary gland	Rattus norvegicus	-
pituitary gland cell line	expression of RALDH2 is located in Rathke's pouch at embryonic day 12.5 and subsequently in the developing anterior pituitary gland. Pituitary RALDH2 mRNA levels are high at E17.5 and decrease markedly after birth	Rattus norvegicus	-
pituitary gland cell line	expression of RALDH3 is located in Rathke's pouch at embryonic day 12.5 and subsequently in the developing anterior pituitary gland. Pituitary RALDH3 mRNA levels are high at E17.5 and decrease markedly after birth	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
retinal + NAD+ + H2O	-	Rattus norvegicus	retinoate + NADH + H+	-	?

Synonyms

Synonyms	Comment	Organism
RalDH1	-	Rattus norvegicus
RALDH2	-	Rattus norvegicus
RALDH3	-	Rattus norvegicus
retinaldehyde dehydrogenase	-	Rattus norvegicus
retinaldehyde dehydrogenase 1	-	Rattus norvegicus
retinaldehyde dehydrogenase 2	-	Rattus norvegicus
retinaldehyde dehydrogenase 3	-	Rattus norvegicus

Cofactor

Cofactor	Comment	Organism	Structure
NADH	-	Rattus norvegicus

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Release 2023.1 (January 2023)