Activating Compound | Comment | Organism | Structure |
---|---|---|---|
apoCRABP | stimulates retinoic acid synthesis by about 30-50% | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
all-trans-retinal | 9-cis-retinoic acid synthesis from 0.002 mM 9-cis-retinal is inhibited 50% by 0.005 mM all-trans-retinal | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Sprague-Dawley, BR strain | - |
Rattus norvegicus BR | - |
Sprague-Dawley, BR strain | - |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | 13-cis-retinal is not an efficient substrate, isomerisation of 13-cis-retinal into all-trans-retinal provides substrate for all-trans retinoic acid synthesis | Rattus norvegicus | ? | - |
? | |
additional information | 13-cis-retinal is not an efficient substrate, isomerisation of 13-cis-retinal into all-trans-retinal provides substrate for all-trans retinoic acid synthesis | Rattus norvegicus BR | ? | - |
? | |
retinal + NAD+ + H2O | enzyme also accounts for about 90% of the 9-cis-retinal dehydrogenase activity | Rattus norvegicus | retinoate + NADH | - |
? | |
retinal + NAD+ + H2O | enzyme also accounts for about 90% of the 9-cis-retinal dehydrogenase activity | Rattus norvegicus BR | retinoate + NADH | - |
? |