Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-alpha-aminoadipate-semialdehyde + NAD(P)+ + H2O | - |
Homo sapiens | L-alpha-aminoadipate + NAD(P)H + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alpha-AASA dehydrogenase | - |
Homo sapiens |
alpha-aminoadipic semialdehyde dehydrogenase | - |
Homo sapiens |
antiquitin | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD(P)+ | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | alpha-AASA dehydrogenase deficiency results in the accumulation of pathognomonic alpha-aminoadipic semialdehyde (in cerebrospinal fluid, plasma and urine) and pipecolic acid (cerebrospinal fluid and plasma) in affected patients | Homo sapiens |