Literature summary for 1.2.1.31 extracted from

Wang, L.; Jil, C.; Xu, Y.; Xu, J.; Dai, J.; Wu, Q.; Wu, M.; Zou, X.; Sun, L.; Gu, S.; Xie, Y.; Mao, Y.
Cloning and characterization of a novel human homolog of mouse U26, a putative PQQ-dependent AAS dehydrogenase (2005), Mol. Biol. Rep., 32, 47-53.

Cloned(Commentary)

Cloned (Comment)	Organism
cDNA is cloned from a human fetal library, library is constructed in a modified pBluescript II SK+ vector, cDNA insert is sequenced	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-2-aminoadipate 6-semialdehyde + NAD(P)+ + H2O	Homo sapiens	-	L-2-aminoadipate + NAD(P)H + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q4L235	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	fetal brain cDNA library	Homo sapiens	-
brain	-	Homo sapiens	-
brain	mRNA expression	Homo sapiens	-
breast cancer cell	-	Homo sapiens	-
colon	-	Homo sapiens	-
colon	mRNA expression	Homo sapiens	-
colonic adenocarcinoma cell	colon adenocarcinoma, GI-112	Homo sapiens	-
colonic adenocarcinoma cell	colon adenocarcinoma, CX-1	Homo sapiens	-
heart	-	Homo sapiens	-
heart	mRNA expression	Homo sapiens	-
kidney	-	Homo sapiens	-
kidney	high mRNA expression	Homo sapiens	-
leukocyte	peripheral blood leukocyte	Homo sapiens	-
liver	-	Homo sapiens	-
liver	high mRNA expression	Homo sapiens	-
lung	-	Homo sapiens	-
lung	mRNA expression	Homo sapiens	-
lung cancer cell	lung carcinoma, GI-117	Homo sapiens	-
lung cancer cell	lung carcinoma, LX-1	Homo sapiens	-
ovary	-	Homo sapiens	-
ovary	mRNA expression	Homo sapiens	-
ovary cancer cell	ovarian carcinoma, GI-102	Homo sapiens	-
pancreas	-	Homo sapiens	-
pancreas	high mRNA expression	Homo sapiens	-
peripheral blood	mRNA expression	Homo sapiens	-
placenta	-	Homo sapiens	-
placenta	mRNA expression	Homo sapiens	-
prostate	-	Homo sapiens	-
prostate adenocarcinoma cell	prostatic adenocarcinoma, PC3	Homo sapiens	-
prostate gland	mRNA expression	Homo sapiens	-
skeletal muscle	low mRNA expression	Homo sapiens	-
skeletal system	-	Homo sapiens	-
small intestine	-	Homo sapiens	-
small intestine	mRNA expression	Homo sapiens	-
spleen	-	Homo sapiens	-
spleen	high mRNA expression	Homo sapiens	-
testis	-	Homo sapiens	-
testis	high mRNA expression	Homo sapiens	-
thymus	-	Homo sapiens	-
thymus	mRNA expression	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-2-aminoadipate 6-semialdehyde + NAD(P)+ + H2O	-	Homo sapiens	L-2-aminoadipate + NAD(P)H + H+	-	?

Synonyms

Synonyms	Comment	Organism
2-aminoadipic 6-semialdehyde dehydrogenase	-	Homo sapiens
human U26	-	Homo sapiens
L-aminoadipate-semialdehyde dehydrogenase	-	Homo sapiens
U26	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
pyrroloquinoline quinone	PQQ	Homo sapiens