Application | Comment | Organism |
---|---|---|
synthesis | synthesis of 3-hydroxypropionic acid. UTR engineering is used to maximally increase the activities of glycerol dehydratase and aldehyde dehydrogenase for the high conversion of glycerol to 3-hydroxypropionic acid. Thereafter, the activity of glycerol dehydratase is precisely controlled to avoid the accumulation of 3-hydroxypropionaldehyde by varying expression of dhaB1, a gene encoding a main subunit of glycerol dehydratase. The optimally balanced Escherichi coli HGL_DBK4 shows a substantially enhanced 3-hydroxypropionic acid titer and productivity compared with the parental strain. The yield on glycerol is 0.97 g 3-hydroxypropionic acid/g glycerol, in a fed-batch experiment | Azospirillum brasilense |
Organism | UniProt | Comment | Textmining |
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Azospirillum brasilense | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
ALDH | - |
Azospirillum brasilense |
General Information | Comment | Organism |
---|---|---|
metabolism | 3-hydroxypropionic acid production pathway from glycerol | Azospirillum brasilense |