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Literature summary for 1.2.1.3 extracted from

  • Luo, L.H.; Seo, J.W.; Heo, S.Y.; Oh, B.R.; Kim, D.H.; Kim, C.H.
    Identification and characterization of Klebsiella pneumoniae aldehyde dehydrogenases increasing production of 3-hydroxypropionic acid from glycerol (2013), Bioprocess Biosyst. Eng., 36, 1319-1326.
    View publication on PubMed
Search for more literature for 1.2.1.3

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21 (DE3) pLysS cells Klebsiella pneumoniae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 x * 55000, SDS-PAGE Klebsiella pneumoniae

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae A6T8Z5
-
-
Klebsiella pneumoniae MCG 78578 A6T8Z5
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Klebsiella pneumoniae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxypropionaldehyde + NAD+ + H2O specific substrate Klebsiella pneumoniae 3-hydroxypropionic acid + NADH + H+
-
 ?
3-hydroxypropionaldehyde + NAD+ + H2O specific substrate Klebsiella pneumoniae MCG 78578 3-hydroxypropionic acid + NADH + H+
-
 ?
additional information no activity with propionaldehyde, butyraldehyde, valeraldehyde, isovaleraldehyde, and furaldehyde Klebsiella pneumoniae ?
-
 ?
additional information no activity with propionaldehyde, butyraldehyde, valeraldehyde, isovaleraldehyde, and furaldehyde Klebsiella pneumoniae MCG 78578 ?
-
 ?

Subunits

Subunits Comment Organism
? x * 55000, SDS-PAGE Klebsiella pneumoniae

Synonyms

Synonyms Comment Organism
ALDH
-
 Klebsiella pneumoniae
NAD+-dependent ALDH
-
 Klebsiella pneumoniae
YneI
-
 Klebsiella pneumoniae

Cofactor

Cofactor Comment Organism Structure
NAD+ the enzyme utilizes both NAD+ and NADP+ as cofactor, but with a preference for NAD+ Klebsiella pneumoniae