Cloned (Comment) | Organism |
---|---|
expressed in Salmonella typhimurium strain TA100 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,6-Dichloro-4-nitrophenol | primarily inhibits isoform ALDH2 (non-competitive), but does not affect isoform ALDH3A1 | Homo sapiens | |
additional information | activities of isoforms ALDH2 and ALDH3A1 are unaffected by pentachlorophenol (up to a concentration of 1 mM) | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
formaldehyde + NAD+ + H2O | - |
Homo sapiens | formate + NADH + H+ | - |
? | |
propionaldehyde + NAD+ + H2O | - |
Homo sapiens | propionate + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ALDH2 | isoform | Homo sapiens |
ALDH3A1 | isoform | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0074 | - |
2,6-Dichloro-4-nitrophenol | isoform ALDH2, in 0.1 M sodium diphosphate buffer (pH 9.5), at 21-23°C | Homo sapiens |