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Literature summary for 1.2.1.3 extracted from

  • Lopez-Sanchez, A.; Floriano, B.; Andujar, E.; Hernaez, M.J.; Santero, E.
    Tetralin-induced and ThnR-regulated aldehyde dehydrogenase and beta-oxidation genes in Sphingomonas macrogolitabida strain TFA (2010), Appl. Environ. Microbiol., 76, 110-118.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.3

Activating Compound

Activating Compound Comment Organism Structure
additional information ThnG activity is not affected by the addition of 0.5 mM coenzyme A or dithiothreitol Sphingopyxis macrogoltabida

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli C41 cells Sphingopyxis macrogoltabida

Protein Variants

Protein Variants Comment Organism
additional information the TFA T-668 mutant is obtained by insertion of a nonpolar KIXX cassette into the NaeI site of thnG, resulting in truncation of the gene beyond codon 169, the mutant shows reduced but clearly evident ALDH activity Sphingopyxis macrogoltabida

Organism

Organism UniProt Comment Textmining
Sphingopyxis macrogoltabida
-
-
-
Sphingopyxis macrogoltabida TFA
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no activity is detected when NADP+ is used as the oxidant instead of NAD+ Sphingopyxis macrogoltabida ?
-
 ?
additional information no activity is detected when NADP+ is used as the oxidant instead of NAD+ Sphingopyxis macrogoltabida TFA ?
-
 ?
pimelic semialdehyde + NAD+ + H2O
-
 Sphingopyxis macrogoltabida ?
-
 ?
pimelic semialdehyde + NAD+ + H2O
-
 Sphingopyxis macrogoltabida TFA ?
-
 ?

Synonyms

Synonyms Comment Organism
NAD+-pimelic semialdehyde-dependent aldehyde dehydrogenase
-
 Sphingopyxis macrogoltabida
ThnG
-
 Sphingopyxis macrogoltabida

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Sphingopyxis macrogoltabida