Literature summary for 1.2.1.3 extracted from

Jelski, W.; Chrostek, L.; Zalewski, B.; Szmitkowski, M.
Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) activity in the sera of patients with gastric cancer (2008), Digest. Dis. Sci., 53, 2101-2105.

Search for more literature for 1.2.1.3

Application

Application	Comment	Organism
medicine	serum levels of aldehyde dehydrogenase are not significantly higher in patients with gastric cancer in comparison with the healthy group	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	men, n = 34, control, age 56 - 70, median 2.953 mU/l, range 1.721 - 6.227 mU/l	Homo sapiens
additional information	-	men, n = 34, gastric cancer, age 58 - 72, median 3.002 mU/l, range 1.734 - 7.038 mU/l	Homo sapiens
additional information	-	total group, n = 55, control, age 53 - 70, median 2.918 mU/l, range 1.635 - 6.227 mU/l	Homo sapiens
additional information	-	total group, n = 55, gastric cancer, age 54 - 72, median 2.983 mU/l, range 1.624 - 7.038 mU/l	Homo sapiens
additional information	-	women, n = 21, control, age 53 - 67, median 2.906 mU/l, range 1.635 - 5.224 mU/l	Homo sapiens
additional information	-	women, n = 21, gastric cancer, age 54 - 70, median 2.968 mU/l, range 1.624 - 6.163 mU/l	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6-methoxy-2-naphthaldehyde + NAD+ + H2O	activity assay	Homo sapiens	6-methoxy-2-naphthoate + NADH + H+	-	?

Synonyms

Synonyms	Comment	Organism
aldehyde dehydrogenase	-	Homo sapiens
ALDH	-	Homo sapiens

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8.5	-	activity assay	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Homo sapiens

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Release 2023.1 (January 2023)