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Literature summary for 1.2.1.3 extracted from

  • Mirabelli, P.; Di Noto, R.; Lo Pardo, C.; Morabito, P.; Abate, G.; Gorrese, M.; Raia, M.; Pascariello, C.; Scalia, G.; Gemei, M.; Mariotti, E.; Del Vecchio, L.
    Extended flow cytometry characterization of normal bone marrow progenitor cells by simultaneous detection of aldehyde dehydrogenase and early hematopoietic antigens: implication for erythroid differentiation studies (2008), BMC Physiol., 8, 13.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.3

Application

Application Comment Organism
medicine findings are useful for basic studies about normal erythropoietic differentiation as well as for enabling the employment of ALDH as a red cell marker in polychromatic flow cytometry characterization of bone marrow from patients with aplastic anemia and myelodysplasia Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
4-diethylaminobenzaldehyde DEAB Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
an aldehyde + NAD+ + H2O Homo sapiens
-
 an acid + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bone marrow
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
an aldehyde + NAD+ + H2O
-
 Homo sapiens an acid + NADH + H+
-
 ?

Synonyms

Synonyms Comment Organism
aldehyde dehydrogenase
-
 Homo sapiens
ALDH
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Homo sapiens