KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0033 | - |
propanal | isoenzyme ALDH-II | Rattus norvegicus | |
0.005 | - |
acetaldehyde | isoenzyme ALDH-II | Rattus norvegicus | |
0.0062 | - |
Glutaraldehyde | isoenzyme ALDH-II | Rattus norvegicus | |
0.017 | - |
3,4-dihydroxyphenyl acetaldehyde | membrane-bound isoenzyme ALDH | Rattus norvegicus | |
0.018 | - |
p-nitrobenzaldehyde | isoenzyme ALDH-II | Rattus norvegicus | |
0.023 | - |
(3,4-dihydroxyphenyl)(hydroxy)acetaldehyde | membrane-bound isoenzyme ALDH | Rattus norvegicus | |
0.026 | - |
5-hydroxyindol acetaldehyde | membrane-bound isoenzyme ALDH | Rattus norvegicus | |
0.03 | - |
NAD+ | isoenzyme ALDH-II | Rattus norvegicus | |
0.038 | - |
NAD+ | isoenzyme ALDH-I | Rattus norvegicus | |
0.05 | - |
Glutaraldehyde | isoenzyme ALDH-I | Rattus norvegicus | |
0.056 | - |
p-nitrobenzaldehyde | membrane-bound isoenzyme ALDH | Rattus norvegicus | |
0.22 | - |
acetaldehyde | isoenzyme ALDH-I | Rattus norvegicus | |
0.5 | - |
propanal | isoenzyme ALDH-I | Rattus norvegicus | |
0.56 | - |
Glutaraldehyde | membrane-bound isoenzyme ALDH | Rattus norvegicus | |
2 | - |
propanal | membrane-bound isoenzyme ALDH | Rattus norvegicus | |
2 | - |
p-nitrobenzaldehyde | isoenzyme ALDH-I | Rattus norvegicus | |
10 | - |
acetaldehyde | membrane-bound isoenzyme ALDH | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
204000 | - |
isoenzyme ALDH-II, gel filtration | Rattus norvegicus |
234000 | - |
isoenzyme ALDH-I, gel filtration | Rattus norvegicus |
237000 | - |
membrane-bound isoenzyme ALDH, gel filtration | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
membrane-bound ALDH, ALDH-I: soluble high Km ALDH, and ALDH-II: low Km ALDH | - |
Purification (Comment) | Organism |
---|---|
membrane-bound ALDH, ALDH-I: soluble high Km ALDH, and ALDH-II: low Km ALDH | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
127 | - |
soluble isoenzyme ALDH-II | Rattus norvegicus |
150 | - |
soluble isoenzyme ALDH-I | Rattus norvegicus |
311 | - |
membrane-bound isoenzyme ALDH | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3,4-dihydroxymandelic aldehyde + NAD+ + H2O | - |
Rattus norvegicus | 3,4-dihydroxymandelate + NADH | - |
? | |
3,4-dihydroxyphenyl acetaldehyde + NAD+ + H2O | - |
Rattus norvegicus | 3,4-dihydroxyphenylacetate + NADH | - |
? | |
5-hydroxyindol acetaldehyde + NAD+ + H2O | - |
Rattus norvegicus | 5-hydroxyindol acetate + NADH + H+ | - |
? | |
acetaldehyde + NAD+ + H2O | - |
Rattus norvegicus | acetate + NADH + H+ | - |
? | |
glutaraldehyde + NAD+ + H2O | - |
Rattus norvegicus | glutarate + NADH | - |
? | |
p-nitrobenzaldehyde + NAD+ + H2O | - |
Rattus norvegicus | p-nitrobenzoate + NADH | - |
? | |
propanal + NAD+ + H2O | - |
Rattus norvegicus | propionate + NADH | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Rattus norvegicus |