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Literature summary for 1.2.1.24 extracted from

  • Leone, O.; Blasi, P.; Palmerio, F.; Kozlov, A.I.; Malaspina, P.; Novelletto, A.
    A human derived SSADH coding variant is replacing the ancestral allele shared with primates (2007), Ann. Hum. Biol., 33, 593-603.
    View publication on PubMed

Application

Application Comment Organism
additional information in the world population, the c.538C variant of SSADH is proceeding to replace the ancestral c.538T, shared with primates. A significant correlation between the frequencies of the derived alleles in SSADH and microcephalin, which show concerted changes worldwide and, at least in Asian populations, also on a restricted geographical scale Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P51649
-
-

Synonyms

Synonyms Comment Organism
SSADH
-
Homo sapiens
succinic semialdehyde dehydrogenase
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Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Homo sapiens