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Literature summary for 1.2.1.24 extracted from
- Succinic semialdehyde dehydrogenase of wheat grain (1978), Planta, 142, 175-180.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| 2-mercaptoethanol | strongly dependent on presence of | Triticum turgidum subsp. durum |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0074 | - |
succinate semialdehyde | - |
Triticum turgidum subsp. durum | |
| 0.2 | - |
NAD+ | - |
Triticum turgidum subsp. durum | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 130000 | - |
gel filtration | Triticum turgidum subsp. durum |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Triticum turgidum subsp. durum | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Triticum turgidum subsp. durum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinate semialdehyde + NAD+ + H2O | - |
Triticum turgidum subsp. durum | succinate + NADH | - |
? | |
| succinate semialdehyde + NADP+ + H2O | activity with NAD+ is about 7fold higher than activity with NADP+ | Triticum turgidum subsp. durum | succinate + NADPH | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 40 | - |
stable up to | Triticum turgidum subsp. durum |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | - |
- |
Triticum turgidum subsp. durum |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 8 | 10 | pH 8.0: about 40% of maximal activity, pH 10.0: about 55% of maximal activity | Triticum turgidum subsp. durum |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 5 | - |
18°C, 1 h, about 20% loss of activity | Triticum turgidum subsp. durum |
| 6 | 9 | 18°C, 1 h, stable | Triticum turgidum subsp. durum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Triticum turgidum subsp. durum | |
| NADP+ | cofactor | Triticum turgidum subsp. durum | |
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Release 2023.1 (January 2023)
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