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Literature summary for 1.2.1.24 extracted from
- Purification and some properties of succinic semialdehyde dehydrogenase from barley seeds (1988), Agric. Biol. Chem., 52, 2929-2930.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5,5'-dithiobis(2-nitrobenzoic acid) | - |
Hordeum vulgare subsp. vulgare |  |
| Cu2+ | - |
Hordeum vulgare subsp. vulgare | |
| Fe3+ | - |
Hordeum vulgare subsp. vulgare | |
| Hg2+ | - |
Hordeum vulgare subsp. vulgare | |
| Pb2+ | - |
Hordeum vulgare subsp. vulgare | |
| PCMB | - |
Hordeum vulgare subsp. vulgare | |
| Zn2+ | - |
Hordeum vulgare subsp. vulgare | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0159 | - |
succinate semialdehyde | - |
Hordeum vulgare subsp. vulgare | |
| 0.166 | - |
NAD+ | - |
Hordeum vulgare subsp. vulgare | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 60000 | - |
4 * 60000, SDS-PAGE | Hordeum vulgare subsp. vulgare |
| 225000 | - |
gel filtration | Hordeum vulgare subsp. vulgare |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Hordeum vulgare subsp. vulgare | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Hordeum vulgare subsp. vulgare |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| seed | - |
Hordeum vulgare subsp. vulgare | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 269 | - |
- |
Hordeum vulgare subsp. vulgare |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinate semialdehyde + NAD+ + H2O | - |
Hordeum vulgare subsp. vulgare | succinate + NADH | - |
? | |
| succinate semialdehyde + NADP+ + H2O | reduction rate is only a few percent of that of NAD+ | Hordeum vulgare subsp. vulgare | succinate + NADPH | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 4 * 60000, SDS-PAGE | Hordeum vulgare subsp. vulgare |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 42 | - |
- |
Hordeum vulgare subsp. vulgare |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
- |
40 | pH 8.9, 10 min, stable | Hordeum vulgare subsp. vulgare |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | - |
- |
Hordeum vulgare subsp. vulgare |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 9 | 4°C, 18 h, stable | Hordeum vulgare subsp. vulgare |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Hordeum vulgare subsp. vulgare | |
| NADP+ | cofactor | Hordeum vulgare subsp. vulgare | |
| NADP+ | reduction rate is only a few percent of that of NAD+ | Hordeum vulgare subsp. vulgare | |
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