Literature summary for 1.2.1.12 extracted from

Omodeo-Sale, F.; Cortelezzi, L.; Riva, E.; Vanzulli, E.; Taramelli, D.
Modulation of glyceraldehyde 3 phosphate dehydrogenase activity and tyr-phosphorylation of Band 3 in human erythrocytes treated with ferriprotoporphyrin IX (2007), Biochem. Pharmacol., 74, 1383-1389.

Search for more literature for 1.2.1.12

Activating Compound

Activating Compound	Comment	Organism	Structure
Ferric protoporphyrin IX	145% increase of activity at 0.04 mM ferric protoporphyrin IX after 30 min exposure to stauroporin	Homo sapiens
H2O2	186% increase of activity at 1 mM H2O2	Homo sapiens
Triton X-100	-	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	stauroporine does not inhibit stimulation of G3PD activity	Homo sapiens
N-acetylcysteine	5 mM N-acetylcysteine significantly reduces G3PD activation induced by both H2O2 and ferric protoporphyrin IX	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Homo sapiens	5829	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
erythrocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-glyceraldehyde 3-phosphate + phosphate + NAD+	-	Homo sapiens	3-phospho-D-glyceroyl phosphate + NADH + H+	-	?

Synonyms

Synonyms	Comment	Organism
G3PD	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)