Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Periodate | - |
Escherichia coli | |
perrhenate | very weak inhibitor | Escherichia coli | |
phosphonate | weak inhibitor | Escherichia coli | |
tellurate | - |
Escherichia coli | |
tungstate | - |
Escherichia coli |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.14 | - |
vanadate | - |
Escherichia coli | |
1.6 | - |
arsenate | - |
Escherichia coli | |
2.9 | - |
phosphate | - |
Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-4-aspartyl phosphate + NADPH | Escherichia coli | - |
L-aspartate 4-semialdehyde + phosphate + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-4-aspartyl phosphate + NADPH | - |
Escherichia coli | L-aspartate 4-semialdehyde + phosphate + NADP+ | - |
? | |
L-aspartate 4-semialdehyde + arsenate + NADP+ | - |
Escherichia coli | ? | - |
r | |
L-aspartate 4-semialdehyde + phosphate + NADP+ | - |
Escherichia coli | L-4-aspartyl phosphate + NADPH | - |
r | |
L-aspartate 4-semialdehyde + vanadate + NADP+ | - |
Escherichia coli | ? | - |
r | |
additional information | the putative phosphate side contains arginine and a lysine that can provide electrostratic attraction to bind an oxyanion | Escherichia coli | ? | - |
? | |
additional information | the kinetic parameters with arsenate are comparable to those of phosphate, vanadate is an excellent substrate for the enzyme | Escherichia coli | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Escherichia coli | |
NADPH | - |
Escherichia coli |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.22 | - |
Periodate | - |
Escherichia coli | |
11 | - |
tellurate | - |
Escherichia coli | |
17 | - |
phosphonate | - |
Escherichia coli | |
26 | - |
tungstate | - |
Escherichia coli | |
140 | - |
perrhenate | - |
Escherichia coli |