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Literature summary for 1.2.1.11 extracted from

  • Jenkins, M.B.; Garner, H.R.
    Studies of a homoserineless bradytroph of Neurospora crassa: demonstration of an altered aspartate beta-semialdehyde dehydrogenase (1967), Biochim. Biophys. Acta, 141, 287-295.
    View publication on PubMed
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KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.02
-
 NADPH mutant Neurospora crassa
0.025
-
 NADPH wild type Neurospora crassa

Organism

Organism UniProt Comment Textmining
Neurospora crassa
-
 wild type strain G165-3A and mutant strain G184-1A
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Neurospora crassa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-aspartate 4-semialdehyde + phosphate + NADP+
-
 Neurospora crassa L-4-aspartyl phosphate + NADPH
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
19
-
 mutant Neurospora crassa
28
-
 above 28°C, wild type Neurospora crassa

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
50
-
 3 min, 50% loss of activity, mutant, 5 min, no loss of activity, wild type Neurospora crassa
65
-
 30 min, wild type, stable Neurospora crassa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4 7.8 mutant Neurospora crassa
8
-
 wild type Neurospora crassa

pH Range

pH Minimum pH Maximum Comment Organism
6.5 9 pH 6.5: about 45% of activity maximum, mutant, about 8% of activity maximum, wild type, pH 9.0: about 55% of activity maximum, mutant, about 30% of activity maximum, wild type Neurospora crassa