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Literature summary for 1.2.1.104 extracted from
- The malaria parasite Plasmodium falciparum has only one pyruvate dehydrogenase complex, which is located in the apicoplast (2005), Mol. Microbiol., 55, 39-53.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| apicoplast | relict plastid, fusion of two-part leader sequence of enzyme to green fluorescent protein confirms apicoplast localization | Plasmodium falciparum | 20011 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Plasmodium falciparum | - |
organism contains only one single enzyme complex | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, presence of 50% glycerol, 10-20 mM beta-mercaptoethanol, stable for months | Plasmodium falciparum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pyruvate + CoA + NAD+ | - |
Plasmodium falciparum | acetyl-CoA + CO2 + NADH | - |
? |  |
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Release 2023.1 (January 2023)
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