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Literature summary for 1.18.1.2 extracted from

  • Yamazaki, M.; Ichikawa, Y.
    Crystallization and comparative characterization of reduced nicotinamide adenine dinucleotide phosphate-ferredoxin reductase from sheep adrenocortical mitochondria (1990), Comp. Biochem. Physiol. B, 96, 93-100.
    View publication on PubMed
Search for more literature for 1.18.1.2

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Ovis aries 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
52000
-
 minimum MW, SDS-PAGE Ovis aries
52300
-
 calculated from amino acid analysis Ovis aries

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NADPH + oxidized ferredoxin Ovis aries first enzyme in mitochondrial P-450-linked monooxygenase system catalyzing several steps in the biosynthesis of steroid hormones, bile acids or vitamin D3 in various tissues NADP+ + reduced ferredoxin
-
 ?
NADPH + oxidized ferredoxin Ovis aries key enzyme catalyzing the electron transport between NADPH generated by pentose phosphate pathway and ferredoxin in plastids of plant heterotrophic tissues NADP+ + reduced ferredoxin
-
 ?

Organism

Organism UniProt Comment Textmining
Ovis aries
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
 Ovis aries
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Ovis aries

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADPH + oxidized ferredoxin
-
 Ovis aries NADP+ + reduced ferredoxin
-
 ?
NADPH + oxidized ferredoxin first enzyme in mitochondrial P-450-linked monooxygenase system catalyzing several steps in the biosynthesis of steroid hormones, bile acids or vitamin D3 in various tissues Ovis aries NADP+ + reduced ferredoxin
-
 ?
NADPH + oxidized ferredoxin key enzyme catalyzing the electron transport between NADPH generated by pentose phosphate pathway and ferredoxin in plastids of plant heterotrophic tissues Ovis aries NADP+ + reduced ferredoxin
-
 ?

Cofactor

Cofactor Comment Organism Structure
FAD flavoprotein Ovis aries
FAD 1 mol FAD per mol of enzyme Ovis aries