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Literature summary for 1.17.4.1 extracted from

  • Xu, H.; Faber, C.; Uchiki, T.; Racca, J.; Dealwis, C.
    Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly (2006), Proc. Natl. Acad. Sci. USA, 103, 4028-4033.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
subunit Rnr1 in complex with gemcitabine diphosphate or with a beta subunit Rnr2 or Rnr4 derived peptide. Binding of gemcitabine diphosphate is different from binding of its analogue CDP. Rnr2 and Rnr4 peptides bind differently from each other and block the formation of the enzyme complex Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P21524
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