Activating Compound | Comment | Organism | Structure |
---|---|---|---|
acetonitrile | - |
Bos taurus | |
dimethylformamide | highly stimulating | Bos taurus | |
dioxane | - |
Bos taurus | |
ethanol | - |
Bos taurus | |
methanol | slightly stimulating | Bos taurus | |
additional information | the enzyme activity is stimulated by organic solvents, but the effect is reduced with increasing temperature, from 27°C to 37°C, the inhibitory effects of all organic solvents on the enzyme activity are increased at higher temperature | Bos taurus | |
Propanol | slightly stimulating | Bos taurus | |
tetrahydrofuran | - |
Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | secreted to milk | Bos taurus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Molybdenum | a molybdenum-containing enzyme | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + O2 + H2O | Bos taurus | - |
urate + H2O2 | - |
? |
Organic Solvent | Comment | Organism |
---|---|---|
additional information | the enzyme activity is stimulated by organic solvents, but the effect is reduced with increasing temperature, from 27°C to 37°C, the inhibitory effects of all organic solvents on the enzyme activity are increased at higher temperature, dependent on pH, overview | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Bos taurus | - |
milk | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + O2 + H2O | - |
Bos taurus | urate + H2O2 | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Bos taurus |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
27 | 50 | - |
Bos taurus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Bos taurus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 9 | - |
Bos taurus |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme plays an important role in the metabolism of many xenobiotics and drugs, such as purines and pyrimidines, mercaptopurine and azathioprine, thiazides, pyrazinamide, and acyclovir | Bos taurus |
additional information | the enzyme also serves as an important biological source of reactive oxygen species that are involved in many pathological processes, such as inflammation, atherosclerosis, cancer, and aging | Bos taurus |