Inhibitors | Comment | Organism | Structure |
---|---|---|---|
febuxostat | i.e. 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylic acid, a non-purine selective inhibitor of xanthine oxidase, an anti-hyperuricaemia drug with low drug-drug interaction potential in clinical use, in vitro drug-drug interaction studies, using ibuprofen, verapamil, nitrendipine, captopril, bezafibrate, warfarin, and digoxin. Febuxostat does not influence the plasma protein binding, and the presence of ibuprofen or warfarin does not change the plasma protein binding of febuxostat of ibuprofen or warfarin, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + H2O + O2 | Homo sapiens | - |
urate + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
xanthine + H2O + O2 | - |
Homo sapiens | urate + H2O2 | - |
? |