Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.17.3.2 extracted from

  • Aranda, R.; Domenech, E.; Rus, A.D.; Real, J.T.; Sastre, J.; Vina, J.; Pallardo, F.V.
    Age-related increase in xanthine oxidase activity in human plasma and rat tissues (2007), Free Radic. Res., 41, 1195-1200.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
xanthine + H2O + O2 Rattus norvegicus old animals show higher enzyme expression and activity than young rats which promotes a worse prognosis for patients with chronic heart failure due to the increased contents of risk factor urate, overview urate + H2O2
-
?
xanthine + H2O + O2 Homo sapiens old persons show higher enzyme expression and activity than young persons which promotes a worse prognosis for patients with chronic heart failure due to the increased contents of risk factor urate, overview urate + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
aorta wall Rattus norvegicus
-
blood positive correlation between plasma xanthine oxidase and age of the individual Homo sapiens
-
plasma positive correlation between plasma xanthine oxidase activity and expression and age of the animal Rattus norvegicus
-
skeletal muscle positive correlation between plasma xanthine oxidase activity and expression and age of the animal Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Homo sapiens
additional information
-
-
Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
xanthine + H2O + O2
-
Homo sapiens urate + H2O2
-
?
xanthine + H2O + O2
-
Rattus norvegicus urate + H2O2
-
?
xanthine + H2O + O2 old animals show higher enzyme expression and activity than young rats which promotes a worse prognosis for patients with chronic heart failure due to the increased contents of risk factor urate, overview Rattus norvegicus urate + H2O2
-
?
xanthine + H2O + O2 old persons show higher enzyme expression and activity than young persons which promotes a worse prognosis for patients with chronic heart failure due to the increased contents of risk factor urate, overview Homo sapiens urate + H2O2
-
?

Synonyms

Synonyms Comment Organism
More formerly EC 1.1.3.22 Homo sapiens
More formerly EC 1.1.3.22 Rattus norvegicus