Literature summary for 1.17.1.9 extracted from

Maia, L.B.; Fonseca, L.; Moura, I.; Moura, J.J.
Reduction of carbon dioxide by a molybdenum-containing formate dehydrogenase: a kinetic and mechanistic study (2016), J. Am. Chem. Soc., 138, 8834-8846.

Search for more literature for 1.17.1.9

Inhibitors

Inhibitors	Comment	Organism	Structure
cyanide	-	Desulfovibrio desulfuricans

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0157	-	CO2	at pH 7.0 and 22°C	Desulfovibrio desulfuricans
0.0571	-	formate	at pH 8.0 and 22°C	Desulfovibrio desulfuricans

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
CO2 + NADH	Desulfovibrio desulfuricans	-	formate + NAD+	-	r
formate + NAD+	Desulfovibrio desulfuricans	-	CO2 + NADH + H+	-	r

Organism

Organism	UniProt	Comment	Textmining
Desulfovibrio desulfuricans	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CO2 + NADH	-	Desulfovibrio desulfuricans	formate + NAD+	-	r
formate + benzyl viologen	-	Desulfovibrio desulfuricans	CO2 + reduced benzyl viologen	-	r
formate + NAD+	-	Desulfovibrio desulfuricans	CO2 + NADH + H+	-	r

Synonyms

Synonyms	Comment	Organism
Mo-FDH	-	Desulfovibrio desulfuricans

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
46.6	-	CO2	at pH 7.0 and 22°C	Desulfovibrio desulfuricans
543	-	formate	at pH 8.0 and 22°C	Desulfovibrio desulfuricans

Cofactor

Cofactor	Comment	Organism	Structure
molybdenum cofactor	-	Desulfovibrio desulfuricans
NAD+	-	Desulfovibrio desulfuricans
NADH	-	Desulfovibrio desulfuricans

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Release 2023.1 (January 2023)