Literature summary for 1.17.1.8 extracted from

Shrivastava, P.; Navratna, V.; Silla, Y.; Dewangan, R.P.; Pramanik, A.; Chaudhary, S.; Rayasam, G.; Kumar, A.; Gopal, B.; Ramachandran, S.
Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues (2016), Sci. Rep., 6, 30827 .

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Cloned(Commentary)

Cloned (Comment)	Organism
the dapB open reading frame is cloned in the expression vector pET28a for expression as N-terminal 6x His-tagged protein	Mycobacterium tuberculosis

Organism

Organism	UniProt	Comment	Textmining
Mycobacterium tuberculosis	P9WP23	-	-
Mycobacterium tuberculosis H37Rv	P9WP23	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+	-	Mycobacterium tuberculosis	(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NADP+ + H2O	-	?
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+	-	Mycobacterium tuberculosis H37Rv	(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NADP+ + H2O	-	?

Synonyms

Synonyms	Comment	Organism
DapB	-	Mycobacterium tuberculosis

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Release 2023.1 (January 2023)