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Literature summary for 1.16.3.1 extracted from
- Discovery of a cytosolic/soluble ferroxidase in rodent enterocytes (2012), Proc. Natl. Acad. Sci. USA, 109, 3564-3569.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| SDS | enzymatic activity inhibited with 1% SDS | Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| enterocyte | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4 Fe(II) + 4 H+ + O2 | - |
Rattus norvegicus | 4 Fe(III) + 2 H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cyto-FOX | - |
Rattus norvegicus |
| cytosolic FOX | - |
Rattus norvegicus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 20 | - |
assay at | Rattus norvegicus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 78 | - |
enzymatic activity is abolished at 78°C | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5 | - |
assay at | Rattus norvegicus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | cytosolic FOX activity increases 30% in iron-deficient rats (compared with controls) but is unchanged in copper-deficient rats | Rattus norvegicus |
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