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Literature summary for 1.16.3.1 extracted from

  • Oosthuizen, M.M.J.; Nei, L.; Myburgh, J.A.; Crookes, R.L.
    Purification of undegraded ceruloplasmin from outdated human plasma (1985), Anal. Biochem., 146, 1-6.
    View publication on PubMed
Search for more literature for 1.16.3.1

Application

Application Comment Organism
medicine homogenous ceruloplasmin with ferroxidase activity for the treatment of aplastic anemics, aplastic anemics have low levels of this enzyme, clinical trials have shown effective in 56% of cases Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
130000
-
 gel filtration, sedimentation equilibrium centrifugation Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fe2+ + H+ + O2 Homo sapiens
-
 Fe3+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.13
-
-
 Homo sapiens

Storage Stability

Storage Stability Organism
4°C, purified enzyme sensitive to storage, no oxidase activity after 4 months Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fe2+ + H+ + O2
-
 Homo sapiens Fe3+ + H2O
-
 ?