Literature summary for 1.16.1.2 extracted from

Sun, I.L.; Toole-Simms, W.; Crane, F.L.; Golub, E.S.; Diaz de Pagan, T.; Morre, D.J.; L�w, H.
Retinoic acid inhibition of transplasmalemma diferric transferrin reductase (1987), Biochem. Biophys. Res. Commun., 146, 976-982.

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Inhibitors

Inhibitors	Comment	Organism	Structure
all-trans retinoic acid	-	Homo sapiens
all-trans retinoic acid	-	Rattus norvegicus
additional information	retinol and retinyl acetate have very little inhibitory effect	Homo sapiens
additional information	-	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasmic membrane	-	Homo sapiens	-	-
cytoplasmic membrane	-	Rattus norvegicus	-	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HeLa cell	-	Homo sapiens	-
liver	-	Homo sapiens	-
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ferritin[Fe(III)] + NADH	-	Homo sapiens	ferritin[Fe(II)] + NAD+	-	?
ferritin[Fe(III)] + NADH	-	Rattus norvegicus	ferritin[Fe(II)] + NAD+	-	?
transferrin[Fe(III)]2 + NADH	-	Homo sapiens	transferrin[Fe(II)]2 + NAD+	-	?
transferrin[Fe(III)]2 + NADH	-	Rattus norvegicus	transferrin[Fe(II)]2 + NAD+	-	?

Cofactor

Cofactor	Comment	Organism	Structure
NADH	-	Homo sapiens
NADH	-	Rattus norvegicus

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Release 2023.1 (January 2023)