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Literature summary for 1.16.1.1 extracted from

  • Tezuka, T.; Someya, J.
    Purification and some properties of mercuric reductase from the organomercury-resistant Penicillium sp. MR-2 strain (1990), Agric. Biol. Chem., 54, 1551-1552.
No PubMed abstract available
Search for more literature for 1.16.1.1

Activating Compound

Activating Compound Comment Organism Structure
2-mercaptoethanol activates, optimal concentration is 3.3 mM Penicillium sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0088
-
 Hg
-
 Penicillium sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
58000
-
 gel filtration Penicillium sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Hg2+ + NADPH Penicillium sp. the enzyme is a key component of an organomercurial detoxification system Hg + NADP+ + H+
-
 ?
Hg2+ + NADPH Penicillium sp. MR-2 the enzyme is a key component of an organomercurial detoxification system Hg + NADP+ + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Penicillium sp.
-
 MR-2 strain
-
Penicillium sp. MR-2
-
 MR-2 strain
-

Purification (Commentary)

Purification (Comment) Organism
-
 Penicillium sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Hg + NADP+ + H+
-
 Penicillium sp. Hg2+ + NADPH
-
 r
Hg + NADP+ + H+
-
 Penicillium sp. MR-2 Hg2+ + NADPH
-
 r
Hg2+ + NADH very little activity with NADH Penicillium sp. Hg + NAD+ + H+
-
 ?
Hg2+ + NADH very little activity with NADH Penicillium sp. MR-2 Hg + NAD+ + H+
-
 ?
Hg2+ + NADPH
-
 Penicillium sp. Hg + NADP+ + H+
-
 ?
Hg2+ + NADPH the enzyme is a key component of an organomercurial detoxification system Penicillium sp. Hg + NADP+ + H+
-
 ?
Hg2+ + NADPH
-
 Penicillium sp. MR-2 Hg + NADP+ + H+
-
 ?
Hg2+ + NADPH the enzyme is a key component of an organomercurial detoxification system Penicillium sp. MR-2 Hg + NADP+ + H+
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 58000, SDS-PAGE Penicillium sp.

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
34
-
-
 Penicillium sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5 8
-
 Penicillium sp.

Cofactor

Cofactor Comment Organism Structure
FAD activity is dependent upon Penicillium sp.
NADH very little activity Penicillium sp.
NADPH
-
 Penicillium sp.