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Literature summary for 1.15.1.1 extracted from

  • Mateo, H.; Marin, C.; Perez-Cordon, G.; Sanchez-Moreno, M.
    Purification and biochemical characterization of four iron superoxide dismutases in Trypanosoma cruzi (2008), Mem. Inst. Oswaldo Cruz, 103, 271-276.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
H2O2
-
Trypanosoma cruzi
additional information no inhiibtion by CN- Trypanosoma cruzi

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol all four isozymes mainly Trypanosoma cruzi 5829
-
mitochondrion isozyme SODIII Trypanosoma cruzi 5739
-
additional information SODI and SODII also occur in low mass organelles Trypanosoma cruzi
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
20000
-
SODI, native PAGE Trypanosoma cruzi
25000
-
SODIV, native PAGE Trypanosoma cruzi
50000
-
SODIII, native PAGE Trypanosoma cruzi
60000
-
SODII, native PAGE Trypanosoma cruzi

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 O2.- + 2 H+ Trypanosoma cruzi
-
O2 + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi
-
-
-

Purification (Commentary)

Purification (Comment) Organism
four isozymes by ammonium sulfate fractionation, anion exchange chromatography, and gel filtration. SODI is purified 424fold, SODII 635fold, SODIII 336fold, and SODIV 489fold Trypanosoma cruzi

Source Tissue

Source Tissue Comment Organism Textmining
epimastigote
-
Trypanosoma cruzi
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
7381
-
purified SODIII Trypanosoma cruzi
9446
-
purified SODI Trypanosoma cruzi
10750
-
purified SODIV Trypanosoma cruzi
13960
-
purified SODII Trypanosoma cruzi

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 O2.- + 2 H+
-
Trypanosoma cruzi O2 + H2O2
-
?

Synonyms

Synonyms Comment Organism
SOD I
-
Trypanosoma cruzi
SODII
-
Trypanosoma cruzi
SODIII
-
Trypanosoma cruzi
SODIV
-
Trypanosoma cruzi

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8
-
assay at Trypanosoma cruzi

pI Value

Organism Comment pI Value Maximum pI Value
Trypanosoma cruzi SODIV, isoelectric focussing
-
3.8
Trypanosoma cruzi SODIII, isoelectric focussing
-
5.2
Trypanosoma cruzi SODII, isoelectric focussing
-
6.8
Trypanosoma cruzi SODI, isoelectric focussing
-
6.9