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Literature summary for 1.14.99.63 extracted from
- Novel beta-carotene ketolases from non-photosynthetic bacteria for canthaxanthin synthesis (2004), Mol. Genet. Genomics, 272, 530-537 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression of DR0093 in the Escherichia coli strain that accumulates beta-carotene results in a carotenoid mixture containing 32% canthaxanthin and 27% echinenone | Deinococcus radiodurans |
| expression of the beta-carotene ketolase gene in an Escherichia coli strain which accumulates beta-carotene results in the production of canthaxanthin | Rhodococcus erythropolis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| beta-carotene + 2 reduced acceptor + 2 O2 | Rhodococcus erythropolis | - |
echinenone + 2 acceptor + 3 H2O | - |
? |  |
| beta-carotene + 2 reduced acceptor + 2 O2 | Deinococcus radiodurans | - |
echinenone + 2 acceptor + 3 H2O | - |
? | |
| beta-carotene + 2 reduced acceptor + 2 O2 | Rhodococcus erythropolis AN12 | - |
echinenone + 2 acceptor + 3 H2O | - |
? | |
| beta-carotene + 2 reduced acceptor + 2 O2 | Deinococcus radiodurans R1 | - |
echinenone + 2 acceptor + 3 H2O | - |
? | |
| echinenone + 2 reduced acceptor + 2 O2 | Rhodococcus erythropolis | - |
canthaxanthin + 2 acceptor + 3 H2O | - |
? | |
| echinenone + 2 reduced acceptor + 2 O2 | Deinococcus radiodurans | - |
canthaxanthin + 2 acceptor + 3 H2O | - |
? | |
| echinenone + 2 reduced acceptor + 2 O2 | Rhodococcus erythropolis AN12 | - |
canthaxanthin + 2 acceptor + 3 H2O | - |
? | |
| echinenone + 2 reduced acceptor + 2 O2 | Deinococcus radiodurans R1 | - |
canthaxanthin + 2 acceptor + 3 H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Deinococcus radiodurans | Q9RY57 | - |
- |
| Deinococcus radiodurans R1 | Q9RY57 | - |
- |
| Rhodococcus erythropolis | Q5IKE4 | - |
- |
| Rhodococcus erythropolis AN12 | Q5IKE4 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| beta-carotene + 2 reduced acceptor + 2 O2 | - |
Rhodococcus erythropolis | echinenone + 2 acceptor + 3 H2O | - |
? | |
| beta-carotene + 2 reduced acceptor + 2 O2 | - |
Deinococcus radiodurans | echinenone + 2 acceptor + 3 H2O | - |
? | |
| beta-carotene + 2 reduced acceptor + 2 O2 | - |
Rhodococcus erythropolis AN12 | echinenone + 2 acceptor + 3 H2O | - |
? | |
| beta-carotene + 2 reduced acceptor + 2 O2 | - |
Deinococcus radiodurans R1 | echinenone + 2 acceptor + 3 H2O | - |
? | |
| echinenone + 2 reduced acceptor + 2 O2 | - |
Rhodococcus erythropolis | canthaxanthin + 2 acceptor + 3 H2O | - |
? | |
| echinenone + 2 reduced acceptor + 2 O2 | - |
Deinococcus radiodurans | canthaxanthin + 2 acceptor + 3 H2O | - |
? | |
| echinenone + 2 reduced acceptor + 2 O2 | - |
Rhodococcus erythropolis AN12 | canthaxanthin + 2 acceptor + 3 H2O | - |
? | |
| echinenone + 2 reduced acceptor + 2 O2 | - |
Deinococcus radiodurans R1 | canthaxanthin + 2 acceptor + 3 H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| beta-carotene ketolase | - |
Rhodococcus erythropolis |
| beta-carotene ketolase | - |
Deinococcus radiodurans |
| CrtO | - |
Rhodococcus erythropolis |
| CrtO ketolase | - |
Rhodococcus erythropolis |
| DR0093 | - |
Deinococcus radiodurans |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | involved in carotenoid synthesis | Rhodococcus erythropolis |
| metabolism | involved in carotenoid synthesis | Deinococcus radiodurans |
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