Cloned (Comment) | Organism |
---|---|
- |
Staphylococcus aureus |
Crystallization (Comment) | Organism |
---|---|
isoform IsdI in complex with heme, heme ruffling and constrained binding of oxygen is consistent with cleavage of the porphyrin ring at the beta- or delta-meso carbon atoms | Staphylococcus aureus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
protoheme + 4 AH2 + 4 O2 | Staphylococcus aureus | - |
15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O | product is a red-orange solid that becomes yellow when dissolved in dimethyl sulfoxide or water/acetonitrile. It is more polar than biliverdin and bilirubin | ? | |
protoheme + 4 AH2 + 4 O2 | Staphylococcus aureus | - |
5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O | product is a red-orange solid that becomes yellow when dissolved in dimethyl sulfoxide or water/acetonitrile. It is more polar than biliverdin and bilirubin | ? | |
protoheme + 4 AH2 + 4 O2 | Staphylococcus aureus N315 | - |
15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O | product is a red-orange solid that becomes yellow when dissolved in dimethyl sulfoxide or water/acetonitrile. It is more polar than biliverdin and bilirubin | ? | |
protoheme + 4 AH2 + 4 O2 | Staphylococcus aureus N315 | - |
5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O | product is a red-orange solid that becomes yellow when dissolved in dimethyl sulfoxide or water/acetonitrile. It is more polar than biliverdin and bilirubin | ? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | Q7A649 | - |
- |
Staphylococcus aureus | Q7A827 | isoform IsdI | - |
Staphylococcus aureus N315 | Q7A649 | - |
- |
Staphylococcus aureus N315 | Q7A827 | isoform IsdI | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
protoheme + 4 AH2 + 4 O2 | - |
Staphylococcus aureus | 15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O | product is a red-orange solid that becomes yellow when dissolved in dimethyl sulfoxide or water/acetonitrile. It is more polar than biliverdin and bilirubin | ? | |
protoheme + 4 AH2 + 4 O2 | - |
Staphylococcus aureus N315 | 15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O | product is a red-orange solid that becomes yellow when dissolved in dimethyl sulfoxide or water/acetonitrile. It is more polar than biliverdin and bilirubin | ? | |
protoheme + 4 AH2 + 4 O2 | - |
Staphylococcus aureus | 5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O | product is a red-orange solid that becomes yellow when dissolved in dimethyl sulfoxide or water/acetonitrile. It is more polar than biliverdin and bilirubin | ? | |
protoheme + 4 AH2 + 4 O2 | - |
Staphylococcus aureus N315 | 5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O | product is a red-orange solid that becomes yellow when dissolved in dimethyl sulfoxide or water/acetonitrile. It is more polar than biliverdin and bilirubin | ? |
Synonyms | Comment | Organism |
---|---|---|
heme oxygenase (staphylobilin-producing) 1 | - |
Staphylococcus aureus |
heme oxygenase (staphylobilin-producing) 2 | - |
Staphylococcus aureus |
isdG | - |
Staphylococcus aureus |
isdI | - |
Staphylococcus aureus |