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Literature summary for 1.14.99.22 extracted from

  • Horike, N.; Sonobe, H.
    Ecdysone 20-monooxygenase in eggs of the silkworm, Bombyx mori: enzymatic properties and developmental changes (1999), Arch. Insect Biochem. Physiol., 41, 9-17.
    View publication on PubMed
Search for more literature for 1.14.99.22

Inhibitors

Inhibitors Comment Organism Structure
KK-42 i.e. 1-benzyl-5[(E)-2,6-dimethyl-1,5-heptadienyl]imidazole Bombyx mori
Metyrapone
-
 Bombyx mori

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Bombyx mori
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ecdysone + NADPH + O2 Bombyx mori
-
 20-hydroxyecdysone + NADP+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Bombyx mori
-
 silkworm
-

Reaction

Reaction Comment Organism Reaction ID
ecdysone + reduced acceptor + O2 = 20-hydroxyecdysone + acceptor + H2O NADPH-dependent monooxygenase containing cytochrome P-450, a heme-thiolate protein Bombyx mori
a

Source Tissue

Source Tissue Comment Organism Textmining
additional information enzyme activity measured in diapause and non-diapause egg subcellular preparations Bombyx mori
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-ecdysone + NADPH + O2
-
 Bombyx mori 20-hydroxyecdysone + NADP+ + H2O
-
 ?
ecdysone + NADPH + O2
-
 Bombyx mori 20-hydroxyecdysone + NADP+ + H2O
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
35
-
-
 Bombyx mori

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Bombyx mori

pH Range

pH Minimum pH Maximum Comment Organism
6 8.5
-
 Bombyx mori

Cofactor

Cofactor Comment Organism Structure
cytochrome P450 essential Bombyx mori
NADPH
-
 Bombyx mori