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Literature summary for 1.14.99.1 extracted from

  • Das, A.; Gogoi, U.; Kalita, J.; Sandilya, S.
    Molecular docking study of a series of substituted xanthone derivatives as novel COX-2 inhibitors targeting prostaglandin endoperoxide synthase-2 (2016), Curr. Enzyme Inhib., 12, 195-204 .
No PubMed abstract available
Search for more literature for 1.14.99.1

Inhibitors

Inhibitors Comment Organism Structure
3,6-bis(3-[[(furan-2-yl)methyl]amino]propyl)-9H-xanthen-9-one
-
 Mus musculus
3,6-bis(5-[[(furan-2-yl)methyl]amino]pentyl)-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[3-(2-methyl-1H-indol-1-yl)propyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[3-(4-methylpiperazin-1-yl)propyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[3-(4-nitroanilino)propyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[3-(cyclohexylamino)propyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[3-(morpholin-4-yl)propyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[3-(piperidin-1-yl)propyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[3-[(1H-pyrazol-3-yl)amino]propyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[3-[(2-chloropyridin-3-yl)amino]propyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[3-[(4H-1,2,4-triazol-4-yl)amino]propyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[3-[(pyrazin-2-yl)amino]propyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[3-[(pyridin-2-yl)amino]propyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[4-(1H-imidazol-2-yl)butyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[5-(2-methyl-1H-indol-1-yl)pentyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[5-(4-methylpiperazin-1-yl)pentyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[5-(4-nitroanilino)pentyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[5-(cyclohexylamino)pentyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[5-(morpholin-4-yl)pentyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[5-(piperidin-1-yl)pentyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[5-[(1H-pyrazol-3-yl)amino]pentyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[5-[(2-chloropyridin-3-yl)amino]pentyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[5-[(4H-1,2,4-triazol-4-yl)amino]pentyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[5-[(piperidin-1-yl)amino]pentyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[5-[(pyrazin-2-yl)amino]pentyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[5-[(pyridin-2-yl)amino]pentyl]-9H-xanthen-9-one
-
 Mus musculus
3,6-bis[6-(1H-imidazol-2-yl)hexyl]-9H-xanthen-9-one
-
 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
arachidonate + reduced acceptor + O2 Mus musculus
-
 prostaglandin H2 + acceptor + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q05769
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonate + reduced acceptor + O2
-
 Mus musculus prostaglandin H2 + acceptor + H2O
-
 ?

Synonyms

Synonyms Comment Organism
COX-2
-
 Mus musculus
prostaglandin endoperoxide synthase-2
-
 Mus musculus