Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-bromo-2-[4-fluorophenyl]-3-[4-methylsulfonylphenyl]-thiophene | DuP-697, selective for isozyme 2 | Homo sapiens | |
Ibuprofen | reversible | Homo sapiens | |
indomethacin | reversible and time-dependent inhibition | Homo sapiens | |
additional information | mechanism of selective inhibition | Homo sapiens | |
N-[2-cyclohexyloxy-4-nitrophenyl]methanesulfonamide | NS-398, selective for isozyme 2 | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.001 | - |
arachidonic acid | isozyme 1 and 2 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
recombinant enzyme, product of COX-2 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonate + electron donor + O2 | - |
Homo sapiens | prostaglandin H2 + oxidized electron donor + H2O | - |
? |