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Literature summary for 1.14.99.1 extracted from
- Further characterization of bovine thyroid prostaglandin synthase (1975), Biochim. Biophys. Acta, 397, 331-341.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| thyrotropin | tissue-specific stimulation in thyroid | Bos taurus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Eicosa-5,8,11,14-tetraynoic acid | - |
Bos taurus |  |
| indomethacin | - |
Bos taurus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.16 | - |
arachidonic acid | - |
Bos taurus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasmic membrane | probably associated with | Bos taurus | - |
- |
| microsome | - |
Bos taurus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| thyroid gland | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| arachidonic acid + AH2 + 2 O2 | - |
Bos taurus | prostaglandin E2 + A + H2O | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
- |
Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 7.3 | formation of prostaglandin E2 from arachidonic acid | Bos taurus |
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