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Literature summary for 1.14.20.13 extracted from

  • Haekkinen, S.T.; Moyano, E.; Cusido, R.M.; Palazon, J.; Pinol, M.T.; Oksman-Caldentey, K.M.
    Enhanced secretion of tropane alkaloids in Nicotiana tabacum hairy roots expressing heterologous hyoscyamine-6beta-hydroxylase (2005), J. Exp. Bot., 56, 2611-2618 .
    View publication on PubMed
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Organism

Organism UniProt Comment Textmining
Hyoscyamus niger P24397
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General Information

General Information Comment Organism
physiological function Agrobacterium-mediated expression in non-hyoscyamine-producing Nicotiana tabacum and hyoscyamine-producing Hyoscyamus muticus. Transgenic Nicotiana tabacum hairy roots show a more efficient uptake of hyoscyamine from the culture medium and a higher rate of bioconversion of hyoscyamine to scopolamine than those of Hyoscamus muticus. The secretion of scopolamine in Nicotiana tabacum hairy roots is up to 85% of the total scopolamine being released to the culture medium. Exogenous hyoscyamine also causes changes in nicotine alkaloid accumulation in Nicotiana tabacum hairy roots Hyoscyamus niger