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Literature summary for 1.14.19.70 extracted from
- Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode (2006), J. Biol. Chem., 281, 39437-39443.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Mycobacterium tuberculosis |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| fluconazole-bound CYP121, sitting drop vapor diffusion method, using 20% (w/v) polyethylene glycol 3350 and 0.2 M NaSCN | Mycobacterium tuberculosis |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| fluconazole | - |
Mycobacterium tuberculosis |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mycobacterium tuberculosis | P9WPP7 | - |
- |
| Mycobacterium tuberculosis H37Rv | P9WPP7 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Mycobacterium tuberculosis |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homohexamer | x-ray crystallography | Mycobacterium tuberculosis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CYP121 | - |
Mycobacterium tuberculosis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| heme | - |
Mycobacterium tuberculosis | |
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