Any feedback?
Literature summary for 1.14.19.63 extracted from
- Cytochrome P450-dependent methylenedioxy bridge formation in Cicer arietinum (1996), Phytochemistry, 41, 457-460.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| O2 | absolutely required for reaction | Cicer arietinum |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| BAS 110 | - |
Cicer arietinum | |
| CO | complete inhibition | Cicer arietinum | |
| cytochrome c | - |
Cicer arietinum | |
| juglone | - |
Cicer arietinum | |
| ketoconazole | - |
Cicer arietinum | |
| N2/O2 | N2/O2 atmosphere (9:1) 15-24% inhibition | Cicer arietinum | |
| Plumbagin | - |
Cicer arietinum | |
| Tetcyclacis | - |
Cicer arietinum | |
| Triadimefone | - |
Cicer arietinum | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0012 | - |
Pratensein | pH 7.5, 12°C | Cicer arietinum | |
| 0.002 | - |
Calycosin | pH 7.5, 12°C | Cicer arietinum | |
| 0.025 | - |
NADPH | pH 7.5, 12°C, 5-hydroxypseudobaptigenin synthesis | Cicer arietinum | |
| 0.025 | - |
NADPH | [reduced NADPH-hemoprotein reductase] | Cicer arietinum | |
| 0.07 | - |
NADPH | pH 7.5, 12°C, pseudobaptigenin synthesis | Cicer arietinum | |
| 0.07 | - |
NADPH | [reduced NADPH-hemoprotein reductase] | Cicer arietinum | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Cicer arietinum | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cicer arietinum | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| calycosin + [reduced NADPH-hemoprotein reductase] + O2 | - |
Cicer arietinum | pseudobaptigenin + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| pratensein + [reduced NADPH-hemoprotein reductase] + O2 | - |
Cicer arietinum | 5-hydroxypseudobaptigenin + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 5-hydroxy-Pss | - |
Cicer arietinum |
| 5-hydroxypseudobaptigenin synthase | - |
Cicer arietinum |
| pseudobaptigenin synthase | - |
Cicer arietinum |
| PSS | - |
Cicer arietinum |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 12 | - |
assay at, facilitates detection of the reactions and yields more product | Cicer arietinum |
| 25 | - |
- |
Cicer arietinum |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Cicer arietinum |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.001 | - |
pH 7.5, 12°C | Cicer arietinum | juglone | |
| 0.0025 | - |
pH 7.5, 12°C | Cicer arietinum | cytochrome c | |
| 0.0045 | - |
pH 7.5, 12°C | Cicer arietinum | Plumbagin | |
| 0.012 | - |
pH 7.5, 12°C | Cicer arietinum | Plumbagin | |
| 0.04 | - |
pH 7.5, 12°C | Cicer arietinum | ketoconazole | |
| 0.06 | - |
pH 7.5, 12°C | Cicer arietinum | ketoconazole | |
| 0.09 | - |
pH 7.5, 12°C | Cicer arietinum | Tetcyclacis | |
| 0.12 | - |
pH 7.5, 12°C | Cicer arietinum | Tetcyclacis | |
| 0.35 | - |
pH 7.5, 12°C | Cicer arietinum | BAS 110 | |
| 0.36 | - |
pH 7.5, 12°C | Cicer arietinum | Triadimefone | |
| 0.4 | - |
pH 7.5, 12°C | Cicer arietinum | BAS 110 | |
| 0.4 | - |
pH 7.5, 12°C | Cicer arietinum | Triadimefone | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
